Bi Liyan, PhD, Associate professor
Faculty Member of School of Special Education
Research Fields
Nanomaterials engineering and biomedical nanotechnology
Representative Research Papers
1. Liyan Bi , Xiao Wang , Xiaowei Cao, Luying Liu, Congcong Bai, Qingyin Zheng, Jaebum Choo, Lingxin Chen, SERS-active Au@Ag core-shell nanorod (Au@AgNR) tags for ultrasensitive bacteria detection and antibiotic-susceptibility testing, Talanta 220 (2020) 121397.
2. Liyan Bi , Yunqing Wang, Ying Yang , Yuling Li, Shanshan Mo, Qingyin Zheng , Lingxin Chen.，Highly sensitive and reproducible SERS sensor for biological pH detection based on uniform gold nanorod array platform，ACS Applied Materials and Interfaces, 2018,10(18): 15381-15387.
3. Liyan Bi, Yanying Rao , Qin Tao , Jian Dong , Ting Su , Fangjing Liu, Weiping Qian. Fabrication of Large-scale Gold Nanoplate Films as Highly Active SERS Substrates for Label Free DNA Detection, Biosensors and Bioelectronics, 2013, 43, 193–199.
4. Liyan Bi, Jian Dong, Wei Xie, Wenbo Lu, Wei Tong, Lin Tao, Weiping Qian. Bimetallic gold-silver nanoplate array as a highly active SERS substrate for detection of Streptavidin/biotin assemblies. Analytica Chimica Acta, 2013, 805, 95-100.
5. Hao Chen, Anupam Das, Liyan Bi, Namhyun Choi, Joung-Il Moon, Yixuan Wu, Sohyun Park and Jaebum Choo, Recent advances in surface-enhanced Raman scattering-based microdevices for point-of-care diagnosis of viruses and bacteria, Nanoscale,2020, 12, 21560–21570.
6. Xiaowei Cao; Zhenyu Wang; Liyan Bi; Caili Bi; Qiu Du; Gold nanocages-based surface-enhanced Raman scattering probes for long-term monitoring intracellular microRNA during bone marrow stem cell differentiation, Nanoscale, 2020(12): 1513-1527.
7. Yue Wang; Xiaoyan Wang; Li Zhang; Yan Huang; Liyan Bi; Changjun Lv; Lingxin Chen; A ratiometric fluorescent probe for detecting the endogenous biological signaling molecule superoxide anion and bioimaging during tumor treatment, Journal of Materials Chemistry B, 2020(8): 1017-1025.
8. Xiaowei Cao, Zhenyu Wang, Liyan Bi, and Jie Zheng. Label-Free Detection of Human Serum Using Surface-Enhanced Raman Spectroscopy Based on Highly Branched Gold Nanoparticle Substrates for Discrimination of Non-Small Cell Lung Cancer, Journal of Chemistry, 2018.
9. Wang Huimei, Shen Shuang, Zheng Tihua, Liyan Bi, Li Bo, Wang Xue, Yang Ying, Jen Philips, The Role of the Dorsal Nucleus of the Lateral Lemniscus in Shaping the Auditory Response Properties of the Central Nucleus of the Inferior Collicular Neurons in the Albino Mouse. Neuroscience. 2018, 15(390): 30-45.
10. Xiaowei Cao, Shuai Chen, Wei Li, Jianfeng Li, Liyan Bi, and Hongcan Shi, One-step synthesis of highly-branched gold nanostructures and its application in fabrication of SERS-active substrates, AIP ADVANCES ,2018,8(10): 105133.
11. Wenbo Lu, Chen Qian, Liyan Bi, Lin Tao, Juan Ge, Jian Dong, Weiping Qian. Biomolecule-based formaldehyde resin microspheres loaded with Au nanoparticles: A novel immunoassay for ultrasensitive detection of tumor markers in human serum. Biosensors and Bioelectronics. 2014, 53: 346–354.
Research Projects
1. National Natural Science Fund, Youth Program, 21605005, A New and Highly efficient Surface-Enhanced Raman Scattering Biosensor used to Detect Antibiotic Resistance of Multiple Pathogens Simultaneously in Bodily Fluids, 01/01/2017-12/31/2020.
2. Shandong Provincial National Natural Science Fund, General Program, ZR202103080072, Application research for SERS detection and target removal of E.coli using target phage nanocomposites, 01/01/2022-12/31/2024.
3. Science and Technology Plan Project for Shandong Universities, J16LK10, Simultaneous detection of drug resistance of multiple pathogens in body fluids based on a new high-efficiency SERS sensor, 01/01/2017-12/31/2020.
