Profile
The Laboratory of Prescription Effect and Clinical Evaluation (hereinafter referred to as the "Laboratory"), based on the Key Laboratory of Shandong Provincial Administration of Traditional Chinese Medicine was jointly being applied by the Binzhou Medical University and Bohai Pharmaceutical Group Co., Ltd., and approved through evaluation in February 2015 to become the first domestic Key Laboratory of State Administration of Traditional Chinese Medicine through university-enterprise cooperation.
The Laboratory, with two major research directions, i.e. the effect of prescription and clinical evaluation, carries out related research, focusing on traditional Chinese medicine clinical experience formula by famous and senior national TCM doctors, the famous varieties of TCM and clinical evaluation of new products of TCM, in order to enhance the technical levels of existing varieties, develop of new agents, explore to solve the problems existing in the study of prescriptions, and provide safe and effective drug for clinical practice.
The Team
At present, the Laboratory has 38 researchers, including 4 Taishan Scholars, 15 professors, 13 associate professors, 19 doctors, 15 masters, 19 under the age of 40, 30 under the age of 50. It is an effective combination of the old, the middle-aged and the young, with the main academic backbone as middle-aged and young scholars. In reasonable professional and age structure, it is a team with strong innovation ability in TCM clinical, TCM industrialization, TCM new drug development, TCM active component analysis, activity evaluation, technology and quality research.
Academic Achievements
Relying on the Laboratory, the team members have undertaken 11 national projects, 16 provincial and ministerial projects, 2 national Torch plans, 1 national SMEs innovation fund project, 17 horizontal projects, and more than 30 million yuan of scientific research funds. It has won 13 provincial and ministerial science and technology awards, published more than 40 academic papers and 13 academic monographs, and applied for 19 invention patents and 14 authorizations.
Infrastructure
At present, the Laboratory has 1000 square meters of drug development process platform and GMP standard laboratory, and 1500 square meters of TCM active component analysis and activity evaluation laboratory. The process platform is equipped with Chinese medicine extraction and concentration unit, ultra-fine grinder, supercritical carbon dioxide extraction, soft capsule production line, oral liquid production line, microwave drying, spray drying, freeze drying, ultrafiltration device, multi-functional granulator and other equipment. The TCM R&D platform is equipped with high-throughput screening instrument, scanning electron microscope, transmission electron microscope, laser confocal microscope, preparative high performance liquid chromatography, Fourier transform infrared spectrometer, flow cytometer and other equipment.
