Collaborative Innovation Center for the Prevention and Treatment of Sleep and Respiratory Diseases

2021-09-28

I. Profile

Actively responding to “The Implementation Plan of the Major Project for Transformation from the Old to the New Drivers for Economic Growth in Shandong Province”, and in-depth implementation of the Healthy Shandong strategy, the Collaborative Innovation Center (hereinafter referred to as the "Center") is jointly established by higher education institutes and enterprises, with Binzhou Medical University as the leading entity, and Yantai University, Bohai Pharmaceutical Co., Ltd., Yuyue Home Textiles and other companies as the co-founder of this Innovation Center.

 

The Center has strengthened university-enterprise cooperation, integrated multi-disciplinary, multi-team collaboration and multi-technology advantages, achieved complementary benefits, resource sharing, and win-win cooperation, and enhanced the integration of technological innovation and industry. It plays a key role in promoting the transformation of medical universities and their affiliated hospitals from separate teaching and medical diagnosis and treatment to medical product research and development and knowledge industrialization. The industrialization of medical knowledge through innovative collaboration between schools and enterprises has promoted the transformation of enterprises from the traditional textile industry to a health industry integrating health care, medical rehabilitation and chronic disease management, achieved cross-industry integration, and promoted transformation of medical knowledge and technology into actual productivity for the prevention and treatment of sleep and respiratory-related diseases, thus providing reference for the construction of smart medical and telemedicine for chronic disease management in Shandong.

 

The Center will focus on five platforms: the development and industrialization of health sleep products related to chronic insomnia, the research and development of smart medical and wearable electronic monitoring equipment, the model promotion of remote home diagnosis and treatment and chronic disease health management, anti-mite and antibacterial series of health medical products, cloud data management and medical service network research and development and promotion.

 

II. The Team

The Center has 3 provincial key laboratories, 1 first-level discipline doctoral degree authorization unit, and 2 provincial key disciplines or clinical key specialties. It has a first-class innovative diagnosis and treatment and product development team for sleep and respiratory-related diseases. The team has 52 staff members, including 43 full-time staff, 9 part-time staff, 10 professors, 9 associate professors, 21 doctoral degree holders, and 7 chief scientists.

 

The Center has a number of interdisciplinary academic teams, a number of key clinical special subject areas, and national and provincial key laboratories. The main members of the team of the Collaborative Innovation Center are well-known scholars at home and abroad in this field. The cooperative units have conducted in-depth research in the prevention and treatment of sleep and breathing related diseases, and have practical experience in undertaking national key, major projects and international cooperation projects. The major breakthroughs made in the research of the Innovation Center projects provide a solid research foundation and guarantee. Yuyue Home Textile Co., Ltd. has a National Certified Laboratory- Shandong Province Ecological Textile Technology Innovation Center, and Shandong Provincial Ecological Textile Engineering Technology Research Center. With good R&D and output capabilities, the company has won two National Science and Technology Progress Awards.

III. Academic Achievements

The collaborative innovation group has undertaken 29 national-level projects, including 4 National 863 Program projects and 14 National Natural Foundation projects; 7 provincial and ministerial-level scientific research projects, including 16 completed projects and 13 on-going projects. More than 60 SCI papers have been published in professional top journals and other foreign journals. It has two second-class awards for National Science and Technology Progress, nine provincial and ministerial and above awards, 83 technical patents, including 42 invention patents and 41 practical new utility patents.

 

A number of smart medical products developed have applied for national patents, including 3D custom pillows, anti-snoring pillows, sleep aid pillows, adaptive pillows, adjustable smart mattresses, antibacterial and anti-mite bedding, far-infrared bedding products that improve microcirculation, sleep monitoring mobile phone software and bracelets, traditional Chinese medicine pillows, personalized custom sleeping products, etc. It achieved turnover of RMB 236.72 million yuan, with an average annual profit of RMB 15.6316 million yuan and a net profit of RMB 11.7237 million yuan.

 

IV. Infrastructure

Binzhou Medical University has two campuses, at Binzhou and Yantai, with a total construction area of 629,000 square meters and a total value of 209 million yuan in teaching and research equipment. Binzhou Medical Univerity Hospital has a construction area of 180,000 square meters and a total asset value of RMB 1.47 billion yuan. It is a center for medicine, teaching, scientific research, health care, and rehabilitation at the Yellow River Delta Regional in North Shandong, of which the Department of Respiratory Medicine, Department of Critical Care Medicine, and Department of Sleep Medicine are all provincial key clinical specialties and key laboratories of the Provincial Department of Health. Among them, the effective use area of the key laboratory of respiration and sleep is more than 1,000 square meters. The clinical part has six independent sleep testing rooms of international standards, which is currently the largest sleep monitoring center in the province. The basic part has 3 animal sleep recording rooms, 3 animal operating rooms, 2 molecular biochemical laboratories, behavior testing rooms, water maze rooms, etc. It has been equipped with the world's most advanced sleep recording, deprivation and analysis hardware and software systems. In addition, the university's central laboratory has large instruments such as high performance liquid chromatography, BD flow cytometer, real-time quantitative PCR, Hitachi electron microscope, Leika laser confocal microscope, and living cell workstation.

 

The original value of existing fixed assets of Yuyue Home Textiles Co., Ltd. was RMB 12.9935 trillion yuan. The company now has innovation platforms such as the State Key Laboratory, the Circular Economy R&D Center of the China National Textile Industry Association, Shandong Academician Workstation, Shandong Ecological Textile Technology Innovation Center, Shandong Provincial Industrial Design Center, and Shandong Provincial Certified Enterprise Technology Center.