Zhang Shumin, PhD, Professor
Research Fields
1. Exploration of Microbial Resources from the Marine Habitats;
2. Natural Products from the Marine Microorganism.
Representative Research Papers
1. Lin Guo, Lu Zhang, Qiaoli Yang, Bo Xu, Xinzhen Fu, Ming Liu, Zhi Li, Shumin Zhang and Zeping Xie. Antibacterial and Cytotoxic Bridged and Ring Cleavage Angucyclinones From a Marine Streptomyces sp. Front. Chem. 2020, 8, 00586.
2. Shu-Min Zhang, Lu Zhang, Li-Juan Kou, Qiao-Li Yang, Bo Qu, Gennaro Pescitelli, Ze-Ping Xie. Isolation, stereochemical study, and racemization of (±)-pratenone A, the first naturally occurring 3-(1-naphthyl)-2-benzofuran-1(3H)-one polyketide from a marine-derived actinobacterium. Chirality. 2020, 32, 299–307.
3. Shumin Zhang, Lu Zhang, Xinzhen Fu, Zhi Li, Lin Guo, Lijuan Kou, Ming Liu and Zeping Xie. (+)- and (−)-actinoxocine, and actinaphthorans A–B, C-ring expansion and cleavage angucyclinones from a marine-derived Streptomyces sp. Org. Chem. Front., 2019, 6, 3925–3928.
4. Qin Yang, Qing-Shou Yao, Yi Kuang, Yue-Zhi Zhang, Ling-Ling Feng, Lu Zhang, Lin Guo, Ze-Ping Xie & Shu-Min Zhang. Antimicrobial and cytotoxic juglones from the immature exocarps of Juglans mandshurica. Nat. Prod. Res. 2019, 33, 3203-3209.
5. Lin Guo, Ze-ping Xie, Qin Yang, Ling-ling Feng, Lu Zhang, Yue-zhi Zhang, Xiao-nian Li, Gennaro Pescitelli, Shu-min Zhang. Kiamycins B and C, unusual bridged angucyclinones from a marine sediment-derived Streptomyces sp. Tetrahedron Lett. 2018, 59(30), 2176−2180.
6. Shumin Zhang, Qin Yang, Lin Guo, Ying Zhang, Lingling Feng, Ling Zhou, Shengxiang Yang, Qingshou Yao, Gennaro Pescitelli and Zeping Xie. Isolation, structure elucidation and racemization of (+)- and (-)-pratensilins A–C: unprecedented spiro indolinone-naphthofuran alkaloids from a marine Streptomyces sp. Chem. Commun., 2017, 53, 10066−10069.
7. Zeping Xie, Ling Zhou, Lin Guo, Xiaoping Yang, Guiwu Qu, Changjing Wu, and Shumin Zhang. Grisemycin, a Bridged Angucyclinone with a Methylsulfinyl Moiety from a Marine-Derived Streptomyces sp. Org. Lett. 2016, 18, 1402−1405.
8. Shumin Zhang, Pingping Xing, Guiping Guo, Hong Liu, Donghai Lin, Chuangchuang Dong, Min Li, and Dongxiao Feng. Development of microbeads of chicken yolk antibodies against Clostridium difficile toxin A for colonic-specific delivery. Drug Deliv. 2016, 23(6), 1940−1947.
9. Lin Wei, Jiuxiang Gao, Shumin Zhang, Sijin Wu, Zeping Xie, Guiying Ling, Yi-Qun Kuang, Yongliang Yang, Haining Yu, and Yipeng Wang. Identification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Antiinflammatory Activity and Special Mechanism. J. Biol. Chem. 2015, 290(27), 16633–16652.
10. Shumin Zhang, Hongyu Zhang, Shengxiang Yang, Chenglei Qu, Zeping Xie and Gennaro Pescitelli. Isolation, Stereochemical Study, and Cytotoxic Activity of Isobenzofuran Derivatives From a Marine Streptomyces sp. Chirality. 2015, 27, 82–87.
11. Guiying Ling, Jiuxiang Gao, Shumin Zhang, Zeping Xie, Lin Wei, Haining Yu, Yipeng Wang. Cathelicidins from the Bullfrog Rana catesbeiana Provides Novel Template for Peptide Antibiotic Design. Plos. One. 2014, 9(3), 1–13.
Research Projects
1. China Torch Program, 2011GH581488, The screening platform construction of new costal bioactive compounds, 01/01/2011-12/31/2013.
2. NSFC-Shandong joint fund project, U1406402-4, Pre-clinical study of antimicrobial peptide HC-C, 06/30/2014-12/31/2016.
3. Shandong Natural Science Fund, General Program, ZR2014hm034, Anti-tumor peptides from the marine actinomycetes from Bohai Bay of China, 12/31/2014-12/31/2017.
Academic Employment
Vice Chairman of Shandong Analysis Society;
Chairman of Biology and Pharmaceutical Branch of Shandong Analysis Society, etc.
